mutagen
المغير
definition
noun
Among the mutagens that have been used to induce mutations, chemical mutagens administered in various ways have become especially popular.
an agent, such as radiation or a chemical substance, that causes genetic mutation.
example
For genetics and breeding, it is fundamentally important to know the germline mutation rate induced by a 'mutagen' .
But we can provoke a quicker second hit by treating the animals with a chemical 'mutagen' or a carcinogen.
One possible explanation for these exceptional findings might be contamination of the ethanol with a 'mutagen' .
These 'mutagens' cause point mutations, because they change the genetic code at one point, so changing a protein's amino acid sequence.
This suggests a 'mutagenic' source different from germ cell replication.
Among the mutagens that have been used to induce mutations, chemical 'mutagens' administered in various ways have become especially popular.
The purpose of this study was to determine if cooked meat containing only moderate concentrations of the known food 'mutagens' would be detectably mutagenic.
Poisons, 'mutagens' , and carcinogens might be created in harmful concentrations.
He was preeminent in the fields of 'mutagenesis' and radiation biology.
Males were fed prior to 'mutagenesis' because starved males did not mate after mutagen treatment.
Cell-culture procedures, chemical 'mutagens' , and radiation all have been applied in what people now refer to as traditional, or conventional, plant breeding for the better part of a century.
According to experimental data, some pesticides and organic solvents are considered potential chemical 'mutagens' .
We show here that these strains can be used to determine very easily the mutagenic specificity of various 'mutagens' .
The integrity and stability of the genetic material is continuously being threatened by endogenous and exogenous factors such as chemical 'mutagens' and radiation.
Significantly, their findings were supported by both in vivo and in vitro experiments using reference 'mutagens' .
Unlike most chemical 'mutagens' , which tend to cause point mutations, rays tend to produce larger aberrations such as chromosome deficiencies or rearrangements.
This cell line detects a wide variety of 'mutagenic' lesions, including point mutations, deletions and various types of chromosomal aberrations.
We and others have shown that studies of 'mutagenesis' in cultured mammalian cells can help predict carcinogenesis.
The so-called Ames test is based on the fact that most carcinogens are 'mutagens' (substances that damage DNA).
A host of carcinogens spew forth, along with poisons, 'mutagens' , and mind-altering drugs.
We carried out several rounds of 'mutagenesis' for each chromosome arm.
Substances which allow the Salmonella to grow are considered 'mutagenic' .
Chemicals that cause changes in DNA sequence, or mutations, are called 'mutagens' .
Lead is clearly not a powerful mutagen, nor is it consistently 'mutagenic' among various test systems.
She devoted her career to an understanding of DNA 'mutagenesis' and the nature of DNA repair mechanisms.
Many carcinogens and mutagens have to be metabolized before their 'mutagenic' activity can be detected.
Detection of low frequency mutations following exposure to 'mutagens' or during the early stages of cancer development is instrumental for risk assessment and molecular diagnosis.
Chemical mutagens and ionizing radiation have long been used as plant 'mutagens' in forward genetic studies.
Exposure to ionizing radiation or environmental 'mutagens' and carcinogens may lead to genomic instability.
Firstly, risks to the descendants of trial participants because of the inadvertent modification of germ cells are not identical to those for chemical 'mutagens' .
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